Clinical significanceClinical indicationsSample typePreparationNotes

Clinical significance
The measles virus belongs to the Paramyxoviridae family. During acute infection, specific class M antibodies (IgM) rise, followed by IgG, which remain for life.

Clinical indications
Suspected infection

Sample type
The patient must have a blood sample taken.

Preparation
You must fast for at least 8 hours; a small amount of water is allowed.

Notes
IgG absent, IgM absent: no exposure. If the clinical picture is uncertain, patients should be monitored over time.
IgG present, IgM absent: past infection.
IgG absent, IgM present: very early stage of infection.
IgG present, IgM present: acute or at least recent infection
The measles virus may cross-react with other paramyxoviruses