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Fusion prostate biopsy

Fusion prostate biopsy is an advanced technique for taking tissue samples from the prostate. Images from a previous multiparametric MRI are “fused” in real time with ultrasound images, so that the needle can be guided precisely to suspicious areas.

Compared with a biopsy guided by ultrasound alone, targeted samples increase the chance of detecting clinically significant cancers.

What it is used for

  • raised or rising PSA levels;
  • an abnormal digital rectal examination;
  • suspicious areas on a multiparametric MRI of the prostate (PI-RADS 3–5);
  • persistent clinical suspicion after a previous negative biopsy;
  • monitoring patients on active surveillance.

How the test is carried out

The procedure is performed by a urologist under local anaesthetic. The fusion software overlays the MRI images on the ultrasound, highlighting the areas to be sampled; targeted samples are then taken, usually together with a few systematic samples from the rest of the gland.

Depending on the technique, access may be transperineal or transrectal. The procedure usually takes 20–30 minutes and the samples are sent for histological examination.

Preparation and precautions

A recent multiparametric MRI of the prostate is required for a fusion biopsy. You will usually also be asked to:

  • have a urine culture, which must be negative;
  • tell us about anticoagulant or antiplatelet treatment, which may need to be stopped or adjusted on your doctor’s advice;
  • follow the antibiotic prophylaxis and any bowel preparation prescribed.

In the following days you may notice a little blood in your urine, semen or stool: this is normal. If you develop a fever, difficulty passing urine or heavy bleeding, contact your doctor straight away.

Services

Fusion prostate biopsy
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*Waiting times refer to working days and to the first available specialist.

CalatafimiMed is in Palermo and is open from Monday to Saturday. For any further information you can contact the centre here.